MICROFLUIDICS
We’ve developed three unique microfluidics platforms to enable integration of sample preparation, nucleic acid amplification, and fluorescence detection of DNA/RNA in instrument platforms — targeting different samples throughout.
These platforms integrate an efficient sample preparation by combining:
chemical, enzymatic and mechanical lysis
rapid DNA/RNA amplification including PCR and isothermal amplification reactions
an accelerated electrophoretic accumulation of DNA/RNA in an array format.
ARRAY TECHNOLOGIES
Electrokinetically enhanced accumulation of DNA/RNA targets on an electrode array and/or on an array of well detection chambers
Carbon Array Technology - low cost, screen printed arrays of electrodes accelerate target accumulation, so the hybridization to specific probes occur within minutes, compared to hours in passive microarrays
Manufacturing technology is as simple as in the glucose sensors, using similar screen printed inks
SAMPLE PREPARATION
The proprietary DNA extraction method combines mechanical, enzymatic, and chemical lysis of nucleic acids
DNA/RNA extraction efficiency is comparable or exceeds current reagents / kits on the market
Sample preparation is completed within 6-8 minutes
ASSAY AND REAGENT KITS
To promote our instrument/cartridge platforms worldwide, we develop assays and assay kits through collaborative ventures offered to partners interested in point-of-care DNA diagnostics
The assays target point-of-use, decentralized and field application markets, as well as R&D and educational molecular biology laboratories
One of our market niche interests is veterinary diagnostics of infectious diseases including pet clinics, high-end equine assays of interest, avian diseases, high consequence bovine, poultry, and swine diseases on farms
Panel assays for: (i) hospital acquired infections; (ii) respiratory viral panels; and (iii) emerging traveller panels, are developed through partnerships
Reagent kits are available for generic sample preparation protocols for extraction of DNA from various samples